The effect of Kremezin to klotho

The effect of Kremezin to klotho - The effect of Kremezin to klotho

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000008351

Enrollment

Registered

2012-07-04

Start date

2012-07-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

chronic kidney disease

Interventions

control observation period 2 years additional internal use of kremezin 6g/day observation period 2years

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 20 years old and over patients of chronic kidney disease( 1.5mg/dL and over sCr 5mg/dL and fewer, and e-GFR 60ml/min./1.73m2 and fewer)

Exclusion criteria

Exclusion criteria: patients of 1.75 years old and over 2.diabetic kidney disease 3.gastrointestinal obstruction 4.poor control of hypertension 5.internal use of ESA or will use of ESA 6.principal investigator dicide to be unsuitable testee

Design outcomes

Primary

Measure	Time frame
The change of klotho	—

Secondary

Measure	Time frame
1.indoxyl sulfate 2.serum creatinine 3.the retio of urine protein/urine creatinine 4.cystatine C	—

Countries

Japan

Contacts

Public ContactShunji Shiohira

Tokyo women's medical university Department of medicine four

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026