Anxiety Disorders, Depressive Disorders
Conditions
Interventions
CBT (Unified Protocol)
Sponsors
National Center of Neurology and Psychiatry, National Center for Cognitive Behavior Therapy and Research
National Disaster Medical Center
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Subjects with current DSM-IV Panic disorder with/without Agoraphobia, Agoraphobia without history of Panic Disorder, Specific Phobia, Social Phobia (Social Anxiety Disorder), Obsessive-Compulsive Disorder, Post-Traumatic Stress Disorder, Generalized Anxiety Disorder, Anxiety Disorder Not Otherwise Specified, Major Depressive Disorder, Depressive Disorder Not Otherwise Specified 2. HAM-D Anxiety Factor >= 7 3. Age 20 years or older, and 65 years or younger at screening. 4. Subjects who give full consent in the participation of the study
Exclusion criteria
Exclusion criteria: 1. No alcohol or substance use disorder in 6 months prior to the screening. 2. No history or concurrent manic or psychotic episode. 3. No other primary DSM-IV Axis I Disorders in six months prior to the screening. 4. No comorbid of antisocial personality disorder. 5. No serious suicidal ideation at screening. 6. Evidence of unable to participate half or more of the intervention phase. 7. No past treatment of CBT. 8. No structured psychotherapy (except supportive therapy) during the intervention. 9. No major cognitive deficits at screening. 10. No life-threatening, severe or unstable physical disorders at screening. 11. Other relevant reason decided by the investigators.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Severity of anxiety symptoms assessed by the SIGH-A (0 week vs 1 week after the completion of intervention) | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Diagnoses assessed by the M.I.N.I. 2. Objective severity of depressive symptoms (GRID-HAM-D) 3. Subjective severity of depressive symptoms (BDI-II) 4. Quality of Life (EuroQol etc) 5. Subjective symptoms for primary diagnosis (self-report scale) 6. Emotion Regulation (ERQ) 7. Experienced Emotion (PANAS) 8. Drop Out rates 9. Adverse Events | — |
Countries
Japan
Contacts
Public ContactNoriko Kato
National Center of Neurology and Psychiatry National Center for Cognitive Behavior Therapy and Research
Outcome results
None listed