The patients who will undergo laryngomicrosurgery for leukoplakia, carcinoma, vocal fold polyp, polypoid and cyst.
Conditions
Interventions
The patients undergo voice rest for 3 days,then start voice therapy from day4 after surgery.They undergo voice therapy for 6weeks. Assessments are needed at 4,12,24weeks.
The patients undergo voice re
Sponsors
Department of Otolaryngology Head and Neck Surgery Graduate School of Medicine Kyoto University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: The subjects are the patients who will undergo laryngomicrosurgery for leukoplakia, carcinoma, vocal fold polyp, polypoid and cyst at Kyoto University Hospital and agree for the participation in this trials.
Exclusion criteria
Exclusion criteria: *the patients with a history of radiation therapy for the larynx. *the patients with a heart or lung disease, who easily become tired upon phonation. *the patients who are pregnant or children. *the patients who cannot follow the doctor's instruction. *the patients who are judged as inappropriate candidates by the doctor.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Stroboscopic examination, aerodynamic assessment, acoustic analysis and voice handicap index(VHI)-10 are performed at 24weeks after surgery. Stroboscopic examination evaluates normalized mucosal wave amplitude(NMWA)and normalized glottal gap(NGG).Aerodynamic assessment includes maximum phonation time(MPT),mean flow rate(MFR) and AC/DC ratio: vocal efficiency index. Acoustic analysis evaluates pitch perturbation quotient(PPQ),amplitude perturbation quotient(APQ),noise to harmonic ratio(NHR).The above parameters are compared between the groups. | — |
Secondary
| Measure | Time frame |
|---|---|
| Same assessments are needed at 4,12,weeks after suegery. | — |
Countries
Japan
Contacts
Public ContactMami Kaneko
Graduate School of Medicine Department of Otolaryngology Head and Neck Surgery
Outcome results
None listed