The clinical intervention trial to post stroke depression and apathy

The clinical intervention trial to post stroke depression and apathy - The clinical intervention trial to post stroke depression and apathy

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000008312

Enrollment

200

Registered

2012-07-08

Start date

2012-07-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post stroke depression and apathy

Interventions

The group which accepts only PSD The paroxetine group The group which accepts only PSD The milnaciplan group The group which accepts only PSD The nicergolin group The group which accepts

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1.Stroke 2.More than GCS13 or less than JCS10 after the first week of the onset 3.Cases to exceed either cut off level of SDS,Apathy score,SADQ-H10 or Vitality index

Exclusion criteria

Exclusion criteria: Contraindication of paroxetine/milnacipran/nicergoline/amantadine/bromocriptine

Design outcomes

Primary

Measure	Time frame
FIM gain FIM efficacy	—

Secondary

Measure	Time frame
Zung Self-Rating Depression Scale gain Apathy Score gain SADQ-H10 gain Vitality index gain	—

Countries

Japan

Contacts

Public ContactTatebayashi Kotaro

Yuaikai Hospital Neurosurgery

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026