Hospitalized and decompensated heart failure
Conditions
Interventions
None listed
Sponsors
MT FUJI study steering committee
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) hospitalized patients for decompensated heart failure with signes of fluid retention and planned tolvaptan use 2) serum Na < 140 mEq/L 3) age: > or = 20 years at the time of informed consent 4) the subject is willing to participate in the study
Exclusion criteria
Exclusion criteria: 1)hemodynamic instability 2)patients with hypersensitivity to study drug or similar compounds 3)anuric patients 4)patients who cannot feel thirst and are difficult to intake the fluid 5)patients are willing to pregnant, potentially pregnant women, pregnant 6)patients have taken tolvaptan 7)acute coronary syndrome 8)adrenal insufficiency 9)scheduled patients underwent coronary angioplasty within the study period 10)the patient regarded as inappropriate for this clinical study by the principal investigator
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| Search for the factors related with the efficacy of tolvaptan therapy and long-term outcome | — |
Primary
| Measure | Time frame |
|---|---|
| Efficacy Safety: adverse events long-term outcome (1year after tolvaptan administration) | — |
Countries
Japan
Contacts
Public ContactNaoki Sato
Nippon Medical School Musashi-Kosugi Hospital Department of Cardiology
Outcome results
None listed