Hepatocellular Carcinoma
Conditions
Interventions
RFA only.
Transcatheter arterial infusion of CDDP(65mg/m2) before RFA.
Sponsors
Kyoundo Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1)Histologically or clinically diagnosed hepatocellular carcinoma. 2)Patients who do not want surgery or other percutaneous local therapy. History of local ablation is limited up to two times. 3)With measurable tumor in the liver, and without extrahepatic metastasis. 4)Performance Status:0-1 5)Child-Pugh:A or B 6)A case the function of the main organ (marrow, kidney, heart) is maintained enough and to meet a standard of the following clinical inspection. 1)WBC:more than 3000/mm3 2)Platelet:more than 5x104/mm3 3)Hb:more than 9.5g/dL 4)serum creatinine:less than 1.2mg/dL 5)BUN:less than 25mg/dL 6)Prothrombin time:more than 50% 7)Total bilirubin:<3.0mg/dL
Exclusion criteria
Exclusion criteria: 1)Severe complications excluding cirrhosis. 2)Active other cancers. 3)History of severe allergy. 4)Pregnant or maybe pregnant, breast-feeding. 5)A case have plan to use interferon during this study period.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| recurrence-free survival, recurrence rate(local, distant) | — |
Countries
Japan
Outcome results
None listed