Effect on durability of bovine pericardial valve after replacement of heart valve

Effect on durability of bovine pericardial valve after replacement of heart valve - ENDURANCE

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000008178

Enrollment

Registered

2012-06-15

Start date

2011-04-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Status post aortic valve replacement with bioprosthetic valve

Interventions

Interventions:Livalo(pitavastatin) Period:3-5years medication:livalo 2~4mg/day control:no medication Period:3-5years

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients who underwent AVR operation using bioprosthetic valve.

Exclusion criteria

Exclusion criteria: hyperlipidemia coronary artery disease malignancy

Design outcomes

Primary

Measure	Time frame
Primary outcomes: Velocity and pressure gradient of bioprosthetic aortic valve (6, 12, 24, 36 months after AVR)	—

Secondary

Measure	Time frame
Secondary outcomes: Calcification score (Agatston score) of bioprosthetic aortic valve (24months after AVR)	—

Countries

Japan

Contacts

Public ContactKumagai Kiichiro

Tohoku University Research Division of Sciences for Aortic Disease

kkumagai@med.tohoku.ac.jp022-717-7222

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026