Effect of the prebiotics taken by pregnant and lactating women on the immunoactive substance in the breast milk and bowel movement

Effect of the prebiotics taken by pregnant and lactating women on the immunoactive substance in the breast milk and bowel movement - The effect of the prebiotics on mothers' milk

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000008142

Enrollment

100

Registered

2012-07-01

Start date

2009-09-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

pregnant woman

Interventions

prebiotics placebo

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: normal pregnant woman

Exclusion criteria

Exclusion criteria: 1. The pregnant woman who need whole body control for toxemia of pregnancy or other diseases during pregnancy progress. 2. The pregnant woman who were judged to be unsuitable from efficacy and safety by doctor.

Design outcomes

Primary

Measure	Time frame
cytokines, IgA and sCD14 in breastmilk	—

Secondary

Measure	Time frame
1. Specific and non specific IgE in mother's blood and umbilical cord blood. 2. Profile of gene expression in white blood cells in breastmilk 3. Changes in bowel habit 4. Changes in intestinal flora of mothers 5. Existence of allergic diseases of chilren at the age of six month	—

Countries

Japan

Contacts

Public ContactNaoki Shimojo

Graduate School of Medicine, Chiba University Pediatrics

043-226-5364

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026