Antispastic efficasy of l-menthol spray on the duodenal mucosa compared with intravenous administration of scopolamine butylbromide for endoscopic retrograde cholangiopancreatography (ERCP)

Antispastic efficasy of l-menthol spray on the duodenal mucosa compared with intravenous administration of scopolamine butylbromide for endoscopic retrograde cholangiopancreatography (ERCP) - Antispastic efficasy of l-menthol compared with scopolamine butylbromide for ERCP

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000008101

Enrollment

200

Registered

2012-06-04

Start date

2012-05-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

biliary tract disease

Interventions

l-mentol spray on the duodenal mucosa during ERCP scopolamine butylbromide intravenous administration during ERCP

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: The study group included patients who required cholangiography. Patients who are planned ERCP. Patients or their family who fully understand and are willing to give a written informed consent about participation.

Exclusion criteria

Exclusion criteria: age 20 years younger; severe heart disease; severe lung disease; prostatic hyperplasia; glaucoma; contraindication to scopolamine butylbromide; pregnant and breast-feeding women or women suspected of being pregnant; women are not willing to avoid pregnancy during the duration of study; acute pancreatitis; chronic pancreatitis with an acute exacerbation; post gastrectomy; biliary cannulation using with Rendezvous method; contrast medium allergy; or refusal to provide informed consent.

Design outcomes

Primary

Measure	Time frame
The primary outcome was the rate of peristalsis suppression of duodenum after treatment.	—

Countries

Japan

Contacts

Public ContactYasuyuki Gen

Kyoto prefectural Yosanoumi hospital Department of gastroenterology and hepatology

y-gen6-4@koto.kpu-m.ac.jp

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026