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Noninvasive Evaluation of Hepatic Hemodynamics Using Xe Computed Tomography

Noninvasive Evaluation of Hepatic Hemodynamics Using Xe Computed Tomography - Hepatic Hemodynamics Using Xe Computed Tomography

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000008078
Enrollment
1000
Registered
2012-06-02
Start date
2001-10-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Liver disease (acute hepatitis, Chronic hepatitis, liver cirrhosis, hepatic failure, etc) Liver tumor (hepatocellular carcinoma, cholangiocellular carcinoma, metastatic liver tumor, etc)

Interventions

1. Patients with liver disease, who can admit to our hospital 2. we used 25 % stable Xe gas in conjunction with an AZ-726 Xe gas inhalation system (Anzai Medical, Tokyo, Japan). The wash-in and wash-

Sponsors

St. Marianna University, School of Medicine, Department of Internal Medicine, Division of Gastroenterology & Hepatology
Lead Sponsor
Anzai Medical Company Ltd
Collaborator

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Inpatients with liver disease or tumor

Exclusion criteria

Exclusion criteria: 1. severe cardiac, renal and lung disease 2. consciouness distubance 3. severe allergy and asthma 4. pregnacy 5. Otherwise, in case that investigators judge the patient who is inappropriate for this study.

Design outcomes

Primary

MeasureTime frame
1. correlation between tissue blood flow and stage of fibrosis. 2. correlation between tissue blood flow and grade of Child-Pugh. 3. correlation between Xe solubility coefficient and stage of steatosis. 4. Alteration of tissue blood flow and Xe solubility coefficient before and after treatment (interferon, endoscopic procedure, operation, diet-exercise therapy, etc)

Secondary

MeasureTime frame
1. reproducibility 2. safety

Countries

Japan

Contacts

Public ContactHideaki Takahashi

St. Marianna University, School of Medicine Department of Internal Medicine, Division of Gastroenterology

hide-bo@marianna-u.ac.jp+81-44-977-8111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026