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Efficacy of conbination therapy of DPP4-inhibitor and alpha-GI for type-2 diabetes patient.

Efficacy of conbination therapy of DPP4-inhibitor and alpha-GI for type-2 diabetes patient. - Efficacy of conbination therapy of DPP4-inhibitor and alpha-GI for type-2 diabetes patient.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000008051
Enrollment
5
Registered
2012-05-29
Start date
2011-03-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

type-2 diabetes mellitus

Interventions

On the first day, each patient receive a dose of alogliptin (25 mg
after a test meal). On the second day, each patient receive alogliptin (25 mg
after a meal) and acarbose (100 mg
immediately before a test meal). On the third day, each patient receive alogliptin (25 mg
after a test meal) and miglitol (50 mg
immediately before a test meal).

Sponsors

Third Department of Internal Medicine, Tokyo Medical University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: type-2 diabetes patient from 20 to 75 years old patient patients who gave informed consent

Exclusion criteria

Exclusion criteria: contraindication for taking alogliptin contraindication for taking acarbose contraindication for taking miglitol

Design outcomes

Primary

MeasureTime frame
Changing of blood Glucose,insulin,glucagon,totalGIP,active form GLP1 levels before and 30,60 and 120 min after food intake.

Countries

Japan

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026