A randomized clinical trial on the efficacy of Goshajinkigan or carbon dioxide rich water bathing on reducing Paclitaxel-induced peripheral neuropathy during neoadjuvant chemotherapy to breast cancer

A randomized clinical trial on the efficacy of Goshajinkigan or carbon dioxide rich water bathing on reducing Paclitaxel-induced peripheral neuropathy during neoadjuvant chemotherapy to breast cancer - A randomized clinical trial on the efficacy of Goshajinkigan or carbon dioxide rich water bathing on reducing Paclitaxel-induced peripheral neuropathy during neoadjuvant chemotherapy to breast cancer

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000008021

Enrollment

Registered

2012-05-23

Start date

2011-01-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

breast cancer

Interventions

Goshajinkigan carbon dioxide rich water bathing control

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: 1)Age:18 to 74 2)Patients with primary breast cancer who are scheduled to receive FEC100 followed by weekly Paclitaxel as neoadjuvant chemotherapy 3)Written informed consent

Exclusion criteria

Exclusion criteria: 1)Diabetes Mellitus, peripheral neuropathy 2)having prior allergy of skin 3)Physician's decision of inappropriateness

Design outcomes

Primary

Measure	Time frame
reducing neuropathy	—

Secondary

Measure	Time frame
adverse event	—

Countries

Japan

Contacts

Public ContactHidemi Kawajiri

Osaka City University Graduate School of Medicine Department of Surgical Oncology

hkawajiri75@yahoo.co.jp06-6645-3838

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026