Randomized study evaluating antiperistaltic effect of L-menthol sprayed onto the colonic mucosa for colonic endoscopic mucosal resection in patients with underlying disease

Randomized study evaluating antiperistaltic effect of L-menthol sprayed onto the colonic mucosa for colonic endoscopic mucosal resection in patients with underlying disease - The RCT analyzing the efficacy of peppermint oil in colonic endoscopic mucosal resection in patients with underlying disease

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000007984

Enrollment

200

Registered

2012-05-18

Start date

2012-05-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colorectal tumors

Interventions

1.6% L-menthol Glucagon

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients who have agreement to our study and undergo endoscopic mucosal resecton using 1.6% L-menthol or glucagon for colorectal tumors with 5mm to 20mm in diameter

Exclusion criteria

Exclusion criteria: Patient who is not able to undergo colonic endoscopic mucosal resection by other organs disorder

Design outcomes

Primary

Measure	Time frame
The rate of endoscopic and histopathological enbloc resection	—

Secondary

Measure	Time frame
The operation time and antiperistaltic effect	—

Countries

Japan

Contacts

Public ContactKen Inoue

Kyoto Prefectural Yosanoumi Hospital Department of Molecular Gastroenterology and Hepatology

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026