Prospective study for the early detection of radiation-induced myocarial damage by nuclear medicine diagnostic imaging

Prospective study for the early detection of radiation-induced myocarial damage by nuclear medicine diagnostic imaging - Early detection of the radiation-induced myocardial damage by nuclear medicine

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000007966

Enrollment

Registered

2012-07-01

Start date

2012-07-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Esophageal cancer

Interventions

Between July 2012 and December 2015, the subjects will undergo nuclear medicine inspection before, 3 month after and 12 months after the completion of radiation therapy. Inspection methods: After admi

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Esophageal cancer has been diagnosed by pathological examination. There is a radical adaptation of irradiation (No distant metastases). Fair ggeneral condition (PS below 2) No history of heart disease. There is written consent of the patient.

Exclusion criteria

Exclusion criteria: History of heart disease History of radiation to the mediastinum Under 20 year old Lactating or pregnant women

Design outcomes

Primary

Measure	Time frame
Confirm the relationship between BMIPP uptake and irradiation dose of the left ventricular myocardium with respect to each segment of the myocardium.	—

Secondary

Measure	Time frame
Clarify the relationship between the decrease of myocardial BMIPP uptake after irradiation and the subsequent cardiac events.	—

Countries

Japan

Contacts

Public ContactKentaro Takanami

Tohoku University Hospital Department of Radiology

takanami@rad.med.tohoku.ac.jp022-717-7312

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026