Endometrial cancer
Conditions
Interventions
One day before surgery, 99mTc-labeled phytic acid is injected with hysteroscopy around and intra-tumor submucosal myometrial layer, and approximately 15 hours later, just prior to operation, lymphosci
Sponsors
Department of Obstetrics and Gynecology, School of Medicine, Keio University
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: (1)Pathologically-diagnosed endometrial cancer patients with no definite matastasis who are scheduled to receive operation including standard retroperitoneal lymph node dissection. (2)Female patients of twenty and over who yield written consent.
Exclusion criteria
Exclusion criteria: (1)Patients suspicious of positive lymph node metastasis on pre-operative CT/MRI images. (2)Patients with other malignancies.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| detecting rate, sensitivity and false negative rate, negative predective value, detecting rate of micrometastasis and isolated tumor cells | — |
Secondary
| Measure | Time frame |
|---|---|
| learning curve of detecting rate and time needed for sentinel nodes, detecting rates and sentinel node distributions depending on detecting methods and injection sites of tracers, diagnostic accuracy of touch smear of sentinel lymph nodes, diagnostic accuracies of metastasis to lymph nodes in pre-operative PET-CT and sentinel lymph nodes. | — |
Countries
Japan
Contacts
Public ContactNobuyuki Susumu
School of Medicine, Keio University Department of Obstetrics and Gynecology
Outcome results
None listed