patients with relapsing polychondritis patients with bronchial asthma healthy volunteers
Conditions
Interventions
Patients with relapsing polychodiritis
Healthy volunteers
Patients with bronchial asthma
Sponsors
St. Marianna University School of Medicine Division of Respiratory and Infectious Diseases, Department of Internal Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients with relapsing chondritis Healthy volunteers Patients with bronchial asthma
Exclusion criteria
Exclusion criteria: 1) Refused informed consent 2) Exacerbation within the last 3 months for bronchial asthma 3) Patients who are pregnant, possibly pregnant, or lactating. 4) Patients with renal failure. (serum creatinine > 2.0 mg/dL, BUN > 30mg/dl) 5) AST or ALT > 100IU 6) Patients with severe diabetes, hyperlipidemia or hyperuricemia 7) Patients who are judged inappropriate by the investigator in charge.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare FeNO between patients with relapsing polychondritis and healthy volunteers, and patients with relapsing polychondritis and bronchial asthma | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Correlation between FeNO2 and subject complaints (mMRC, Borg scale and VAS) 2. Correlation between FeNO and pulmonary function tests (spirometry and IOS) 3. Correlation between FeNO and eosinophil in sputum 4. Correlation between FeNO and CRP, ESR and MMP-3 5. Variation coefficient of FeNO | — |
Countries
Japan
Contacts
Public ContactHiroshi Handa
St. Marianna University School of Medicine Respiratory and Infectious Diseases, Department of Internal Medicine
Outcome results
None listed