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Genomic analysis approach to avoid from complications from proton pump inhibitor and warfarin combination therapy after open heart surgery

Genomic analysis approach to avoid from complications from proton pump inhibitor and warfarin combination therapy after open heart surgery - Genomic analysis for order made prescription after open heart surgery

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
JPRN
Registry ID
JPRN-UMIN000007826
Enrollment
120
Registered
2012-04-30
Start date
2010-06-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

ischemic heart disease, heart valve disease, atrial fibrillation

Interventions

None listed

Sponsors

Nihon university school of medicine
Lead Sponsor
Sekino clinical Pharmacology Clinic
Collaborator

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: must be administrated warfarin and proton pump inhibitor after open heart surgery

Exclusion criteria

Exclusion criteria: none

Design outcomes

Primary

MeasureTime frame
INR value is 3.5 or more. INR value is 1.5 below even if administrated 5mg of warfarin occurring bleeding event occurring thromboembolic event

Countries

Japan

Contacts

Public ContactKimura Haruka

Nihon university school of medicine Cardiovascular surgery

permanentfixture@gmail.com03-3972-8111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026