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A Randamized, Prospective and Comparative Study of Topical Timolol and Latanoprost in Uveitic Glaucoma

A Randamized, Prospective and Comparative Study of Topical Timolol and Latanoprost in Uveitic Glaucoma - A Comparative Study of Topical Timolol and Latanoprost in Uveitic Glaucoma

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000007820
Enrollment
120
Registered
2012-04-23
Start date
2008-02-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Uveitic Glaucoma

Interventions

Latanoprost eye drop Timolol-XE eye drop

Sponsors

Deportment of Ophthalmology, University of Tokyo Hospital
Lead Sponsor
Department of Ophthalmology, Teikyo University Hospital
Collaborator

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1)The patients received topical corticosteroid for uveitis. 2) There was no strong inflammation in the anterior chamber within these 3 months. 3) The objective eyes didn't received anti-glaucoma eye drops. 4) 30mmHg> Baseline IOP (before starting treatment) >=21mmHg

Exclusion criteria

Exclusion criteria: 1) herpetic iritis 2) PAS index>25% (secondary angle closure glaucoma) 3) The patients who received Argon Laser Trabeculoplasty within 3 months. 4) The patients who received intraocular surgeries within 6 months. 5)The patients who had asthma or arrythmia, and couldn't receive timolol.

Design outcomes

Primary

MeasureTime frame
intraocular pressure-lowering ratio

Secondary

MeasureTime frame
1)flare value in the anterior chamber 2)side effects(conjunctival injection, corneal erosion) 3)macular thickness measured by OCT

Countries

Japan

Contacts

Public ContactToshikatsu Kaburaki

University of Tokyo Hospital Ophthalmology

kabutosi-tky@umin.ac.jp03-3815-5411

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026