patient in whom infliximab is indicated(rheumatoid arthritis, Crohn'
Conditions
Sponsors
Chiba University Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1)infliximab-maintenance treatment adequate case, who are already successfully administrated with usual 2hr infuion without infusion reaction at three and more initial treatment. 2)Adequate organ fanction, no hematological disorder 3)Written informed consent
Exclusion criteria
Exclusion criteria: 1)active serious infection 2)active tuberuculosis infection 3)past history of bronchial asthma 4)past history of hypersensitivity reaction and/or allergy for any drugs and food 5)allergy and/or hypersensitivity for mouse-derived protein 6)demyelinating disease(MS) 7)congestive heart failure 8)pregnant, nursing or likelihood of pregnancy woman 9)unable to birth control during and after 6 months from the latest infliximab administration 10)past treatment history with infliximab and readministration at an interval of over three months 11)Not suitable for participating in the study for any other reason
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of infusion reaction with 60min infliximab accelated infusion | — |
Secondary
| Measure | Time frame |
|---|---|
| 1) patients preference 2) discontinuous rate due to infusion reaction 3) success rate of rescue by usual 2hrs infusion after occurrence of infusion reaction 4) evaluation of premedication | — |
Countries
Japan
Contacts
Public ContactEmiko Sakaida
Graduate School of Medicine, Chiba University Department of Medical Oncology
Outcome results
None listed