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Impact of pregabalin in chronic neuropathic pain after lung resection

Impact of pregabalin in chronic neuropathic pain after lung resection - Impact of pregabalin in chronic neuropathic pain after lung resection

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000007757
Enrollment
200
Registered
2012-04-14
Start date
2011-11-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

All diseases required lung resection

Interventions

Control group pain control with loxoprofen and epidural anesthesia 1) Loxoprofen dose 180mg for daily total dose, 60mg for a dose 2) Epidural anesthesia using fentanil, ropivacaine and sal

Sponsors

Department of General Thoracic and Cardiovascular Surgery, University of Toyama
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients with resected lung

Exclusion criteria

Exclusion criteria: # estimated glomerular filtration rate 30 ml/min and under # median sternotomy approach # preoperative neuropathic pain # pneumonectomy # severe complication (ex. heart failure, renal failure, hepatic failure, ileus) # a woman during pregnancy or lactation, at risk fo becoming pregnant and desired pregnancy by a partner # with psychiatric disorder and difficulty of participation # attending judgement as inappropriateness of participation

Design outcomes

Primary

MeasureTime frame
Visual Analogue Scale on post-operative three month

Secondary

MeasureTime frame
# Visual Analogue Scale on one week, two week, one month, two month after operation # Respiratory function by spirometry on one month, two month, three month after operation. # Checking if a patient has dry cough on one week, two week, one month, two month, three month after operation # Cough medicine on one week, two week, one month, two month, three month after operation # Athene ansomina scale on one week, two week, one month, two month, three month after operation # Hospital periods after operation # Side effect # The number of pain rescue

Countries

Japan

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026