The examination of the relations with sleep disturbance and the prognosis for the bipolar disorder

The examination of the relations with sleep disturbance and the prognosis for the bipolar disorder - The examination of the relations with sleep disturbance and the prognosis for the bipolar disorder

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000007748

Enrollment

Registered

2013-03-31

Start date

2012-04-11

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

The insomnia patients with bipolar disorder diagnosised by DSM, and more 6 points of Pittsburgh Sleep Quality Index

Interventions

Olanzapine medication group Aripiprazole medication group Flunitrazepam medication group

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: The patients of bipolar disorder diagnoded by DSM, and who had the insomnia with more 6 points of Pittsburgh Sleep Quality Index.

Exclusion criteria

Exclusion criteria: The patients with a history of hypersensitivity for olanzapine, aripiprazole,flunitrazepam. The patients with serious hepatic disorder. The patients with diabetes, the patients with a history of diabetes. The patients with acute narrow-angle glaucoma. The patients with myasthenia gravis. The women with during the pregnancy or the possibility to pregnancy.

Design outcomes

Primary

Measure	Time frame
Young Mania Rating Scale Pittsburgh Sleep Quality Index Hamillton Depression Scale	—

Secondary

Measure	Time frame
sleep scan clock gene RNA expression	—

Countries

Japan

Contacts

Public ContactKenichi Osada

St. Marianna University School Of Medicine Neuropsychiatry

k2osada@marianna-u.ac.jp044-977-8111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026