breast cancer
Conditions
Sponsors
Graduate school of medicine,Chiba University
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: Female patients with 1)Histologically confirmed invasive breast cancer patients 2)Lymph node metastases 3)Radical cure by operation 4)PS 0-2 5)Age>=20 6)No prior treatment for breast cancer 7)Required baseline laboratory data within 14days of registration Hb>=8.0g/dL WBC>=3000/mm3 and <=12000mm3 Neu>=2000/mm3 Plt>=100000/mm3 T-Bil<=1.5mg/dL AST,ALT<100IU/L Cre<=1.5mg/dL 8)Written informed consent
Exclusion criteria
Exclusion criteria: 1)Serious drug hypersensitivity 2)Other any cancer 3)Other severe complications 4)Symptomatic brain metastasis 5)Severe mental disorders 6)Active bleeding of digestive tract 7)Serious myeloablation,renal insufficciency,liver failure 8)Massive hydrothorax or ascites 9)Diarrhea 10)Active infection 11)Allergy of the Nab-paclitaxel,paclitaxel or albumin 12)Pregnant 13)Serious Docetaxel and Polysorbate-80 hypersensitivity 14)Not suitable for participating in the study for any other reason
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Completion rate | — |
Secondary
| Measure | Time frame |
|---|---|
| Safety,RDI,DFS | — |
Countries
Japan
Contacts
Public ContactMasahiro Sakakibara
Graduate school of medicine,Chiba University Department of General Surgery
Outcome results
None listed