Open trial of papaverine for treatment-resistant schizophrenia

Open trial of papaverine for treatment-resistant schizophrenia - Papaverine Open Trial

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000007692

Enrollment

Registered

2012-04-08

Start date

2012-04-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Treatment-resistant schizophrenia

Interventions

Additional administration of papaverine.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients with Treatment-resistant schizophrenia.

Exclusion criteria

Exclusion criteria: Patients who are supposed to be in danger with papaverine.

Design outcomes

Primary

Measure	Time frame
Change of PANSS score.	—

Secondary

Measure	Time frame
Change of DIEPSS score.	—

Countries

Japan

Contacts

Public ContactShigenori Tadokoro

Chiba-university Hospital Department of Psychiatry

tadokoroshigenori@gmail.com

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026