Chronic renal failure
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.hemodialysis duration is more than 12 months 2.patients who need erythropoiesis stimulating agents (ESA), more than Darbepoetin alfa 15 or epoetin beta 3000 per week 3.patients who gave written informed consent prior to enrollment
Exclusion criteria
Exclusion criteria: 1.patients with a histry of oral levocarnitine chloride including carnitine supplements on the market 2.female patients who are pregnant, nursing or suspected of pregnancy 3.unsuitable patients
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1.Serum Asymmeteric dimethylarginen (ADMA) 2.Serum Fatty acid bindingprotein (FABP)3,4 and 5 | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.Serum Acyl carnitine and Free carnitine 2.Plasma Brain natriuretic peptide 3.Serum Cardiac Troponin T 4.Echocardiography 5.Electrocardiogram 6.Cardiothoracic ratio in chest X ray photograph 7.Erithropoietic resistance index | — |
Countries
Japan
Contacts
Seseragi Hospital Internal medicine