the cancer inpatient treated with opioids
Conditions
Interventions
Daikenchuto manufactured by Tsumura &
Co. 7.5g/day for a week
only standard therapy
Sponsors
Department of Primary Care and Medical Education, Graduate School of Comprehensive Human Sciences, University of Tsukuba
Tsukuba central hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: From April 2012 to September 2013, among on time admitted cancer adult patients treated with opioid before or newly applied opioid after admission in Tsukuba central hospital palliative care unit, the patient can take orally or tubal feeding, and has under the criterion about satisfaction of defecation scale(visual analogue scale < 70mm)
Exclusion criteria
Exclusion criteria: 1 PPI(Palliative Prognostic Index)>6 scores 2 visual efect 3 pregnant and nursing woman 4 liver disorder(liver enzyme more than five times the upper limit of normal) 5 renal disorder(serum creatinine more than two times the upper limit of normal) 6 gastrointestinal obstruction(diagnosed by CT or MRI and so on. But except bypass operation or colostomy at appropriate site) 7 chemotherapy within a month 8 abdominal operation within a month 9 no patient consent 10 researchers judge inappropriate patient(describe the reason)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| satisfaction of defecation | — |
Secondary
| Measure | Time frame |
|---|---|
| symptom scales for abdominal distension, abdominal pain and loss of appitite, QOL scale, rate of patient had spontaneous defecation more than two times per week, Japanese constipation assessment scale, average of defecation day per week, average of rescue laxative use | — |
Countries
Japan
Contacts
Public ContactKazuhiro Nakazawa
The Graduate School of Comprehensive Human Sciences, University of Tsukuba Primary Care and Medical Education
Outcome results
None listed