Spinal cord injury
Conditions
Sponsors
Department of plastic surgery, Kitano hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Patient whose ASIA classification is A, B or C (at the time of registration) 2. Patient who can participate in the study between 3 weeks and 1 year after injury (at the time of registration) 3. Patient who has partial damage in the spinal cord diagnosed by MR imaging 4. Patient who has provided written informed consent to participate in the study
Exclusion criteria
Exclusion criteria: 1. Patient whose spinal cord is transected completely 2. Patient with central spinal cord injury 3. Patient whose SOFA score is more than 3 (at the time of registration) 4. Patient with hepatitis B, hepatitis C, HIV, ATL,or papovavirus B19 5. Patient with malignant tumor within 5 years before registration 6. Patient with myeloproliferative disease Patient with myelodysplastic syndrome Patient with ischemic heart disease, difficult to control Patient with autoimmune disease Patient with spinal canal stenosis Patient with motor paralysis in the extremities due to the dysfunction of central nervous system before spinal cord injury Patient with hepatic dysfunction Patient with renal failure Patient with psychological diseases, difficult to control 7. Patient with history of participation of other clinical researches within 6 months before registration Patient who is a participant in other studies 8. Patient who is pregnancy or suspicion of pregnancy 9. Patient who is judged to be inappropriate as a participant in this study by researchers
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Type and grade of adverse events Frequency of adverse events | — |
Secondary
| Measure | Time frame |
|---|---|
| To investigate the recovery of motor and sensory function after transplantaion of bone marrow-derived mononuclear cells into cerebrospinal fluid of patients with subacute spinal injury | — |
Countries
Japan
Contacts
Public ContactYoshihisa Suzuki
The Tazuke Kofukai Medical Research Institute, Kitano Hospital Plastic surgery, 5th laboratory
Outcome results
None listed