Effect of pregabarin for intercostal neuralgia associated with Stoney incision after thoracic aortic replacement

Effect of pregabarin for intercostal neuralgia associated with Stoney incision after thoracic aortic replacement - PRETH study

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000007590

Enrollment

Registered

2012-04-01

Start date

2012-04-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

thoracic aortic aneurysm requiring Stoney incision

Interventions

pregabarin 150mg/day for 30 days placebo for 30 days

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: patients undergoing thoracic aortic repair through a Stoney incision

Exclusion criteria

Exclusion criteria: -pregnant woman -less than 40 mm of maximal level of visual analogue scale (VAS) for 4 days following extubation (cf. )(0 mm, no pain; 100 mm, worst pain imaginable) -diabateic patietns with neuropathy -patients with neuropathy from organic brain syndrome -allergy to pregabalin -patients with severe liver dysfuntion (CTCAE grade 3 or 4) -patients who have taken analgesic regularly -patient who does not consent to this study -patient who is deemed by a physician to be unsuitable for study entry

Design outcomes

Primary

Measure	Time frame
Change in pain score (Visual Analog Scale; VAS) between pre- and post-medcation	—

Countries

Japan

Contacts

Public ContactSatoshi Matsuo

Tohoku University Graduate School of Medicine Division of Cardiovascular Surgery

a0mb1082-thk@umin.ac.jp022-717-7222

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026