The effects and side effects of oxytocin: a randomized double-blind comparison of intramyometrial oxytocin and intravenous oxytocin during elective Cesarean section

The effects and side effects of oxytocin: a randomized double-blind comparison of intramyometrial oxytocin and intravenous oxytocin during elective Cesarean section - The effects and side effects of oxytocin: a randomized double-blind comparison of intramyometrial oxytocin and intravenous oxytocin during elective Cesarean section

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000007577

Enrollment

Registered

2012-03-28

Start date

2012-04-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Elective Cesarean section

Interventions

Immediately after delivery of the baby and cord clamping, the obstetrician gives a 2mL intramyometrial test drug (0.07unit/kg oxytocin plus normal saline). At the same time, an anesthesiologist gives

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: ASA physical status 1 or 2, gestational age of over 36 weeks, elective Cesarean section

Exclusion criteria

Exclusion criteria: More than two previous Cesarean sections, previous post-partum hemorrhage, known placenta previa, twin pregnancy, polyhydramnios, pregnancy induced hypertension

Design outcomes

Primary

Measure	Time frame
The lowest systolic blood pressure and the highest heart rate within ten minute after the administration of oxytocin	—

Secondary

Measure	Time frame
Uterine tone assessed by obstetricians Blood loss during operation The rate of patients administered additional uterotonics within 24hour after baby delivery The adverse effects of oxytocin (nausea, vomiting, facial flushing)	—

Countries

Japan

Contacts

Public ContactChieko Akinaga

Hamamatsu University School of Medicine Department of Anesthesiology and Intensive Care Medicine

053-435-2286

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026