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Effectiveness of Bio Glue in reinforcing the aortic stump of acute aortic dissection

Effectiveness of Bio Glue in reinforcing the aortic stump of acute aortic dissection - Effectiveness of Bio Glue in reinforcing the aortic stump of acute aortic dissection

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000007558
Enrollment
80
Registered
2012-03-23
Start date
2012-03-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute aortic dissection

Interventions

In acsending aortic replacement for acute aortic dissection, we focused on the distal anastomosis. After establishment of extracorporeal circulation and selective cerebral perfusion, we reinforce the
Bio Glue group We inject Bio Glue to the false lumen under circulatory arrest for five miutes. Thereafter standard aortic stump formation is performed. Interrupted horizontal mattress sutures fix the

Sponsors

Yokohama City University Medical Center
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Emergent surgery for Stanford type A acute aortic dissection (1)all age, male and female (2)dissection extend to descending aorta (3)Patients' consent

Exclusion criteria

Exclusion criteria: inappropriate patients depend on doctor's judgement

Design outcomes

Primary

MeasureTime frame
Anastomotic leakage to the false lumen

Secondary

MeasureTime frame
Evaluation of effectiveness Intraoperative bleeding Operation time Circuratory arrest time Time for hemostasis Transfusion Maximal diameter of aortic arch at one year after operation Evaluation of safety Operative mortality Stroke, paraplegia, embolization anastomotic lealage,deformation at one year after operation Aortic event

Countries

Japan

Contacts

Public ContactKeiji Uchida

Yokohama City University Medical Center cardiovascular surgery

uchida@urahp.yokohama-cu.ac.jp045-261-5656

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026