A randomized controlled trial of cognitive behavior therapy as an adjunct to usualcare for social anxiety disorder refractory to initial SSRI treatment

A randomized controlled trial of cognitive behavior therapy as an adjunct to usualcare for social anxiety disorder refractory to initial SSRI treatment - CBT for SAD refractory to SSRI- Effectiveness of CBT adjunct usual care

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000007552

Enrollment

Registered

2012-03-30

Start date

2012-06-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Social Anxiety Disorder, Social Phobia

Interventions

cognitive behavioral therapy usual care only

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Primary diagnosis of social anxiety Disorder refractory to initial SSRI treatment (Taking antidepressant treatment and had done so for at least 12 weeks at an adequate dose while remaining at least moderately ill (LSAS > 50). Aged 18 to 75 years

Exclusion criteria

Exclusion criteria: psychosis, major depression, bipolar, active suicidality, organic brain disorder, substance abuse or dependence, antisocial personality disorder, other severe mental / physical condition

Design outcomes

Secondary

Measure	Time frame
Social Phobia and Anxiety Inventory: SPAI Beck Depression Inventory: BDI Clinical Global Impression-Severity: CGI-S Clinical Global Impression-Improvement: CGI-I Seehan Disability Scale: SDS World Health Organization Quality of Life: WHOQOL Euro QOL-5 Dimensions: EQ-5D fMRI (exploratory outcome) <For long-term outcome> Liebowtz Social Anxiety Scale: LSAS (Self-reported) Patient Health Questionnaire-9: PHQ-9 Generalized Anxiety Disorder-7: GAD-7 Euro QOL-5 Dimensions: EQ-5D	—

Measure

Time frame

Social Phobia and Anxiety Inventory: SPAI Beck Depression Inventory: BDI Clinical Global Impression-Severity: CGI-S Clinical Global Impression-Improvement: CGI-I Seehan Disability Scale: SDS World Health Organization Quality of Life: WHOQOL Euro QOL-5 Dimensions: EQ-5D fMRI (exploratory outcome) <For long-term outcome> Liebowtz Social Anxiety Scale: LSAS (Self-reported) Patient Health Questionnaire-9: PHQ-9 Generalized Anxiety Disorder-7: GAD-7 Euro QOL-5 Dimensions: EQ-5D

—

Primary

Measure	Time frame
Liebowtz Social Anxiety Scale: LSAS (assessor-rated)	—

Countries

Japan

Contacts

Public ContactNaoki Yoshinaga

Graduate School of Medicine Chiba University Department of Cognitive Behavioral Physiology

yoshinaga.n@hospital.chiba-u.jp043-226-2027

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026