Study of influential factor to responsiveness of Tolvaptan in patients with volume overload heart failure -Multicenter prospective observational study-

Study of influential factor to responsiveness of Tolvaptan in patients with volume overload heart failure -Multicenter prospective observational study- - Tolvaptan Registry

Status

Recruiting

Phases

Phase 4

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000007551

Enrollment

100

Registered

2012-04-01

Start date

2011-08-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

congestive heart failure

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1.Hospitalized patients at the start of administration of Tolvaptan tablets 2.Patients who takes existing diuretic

Exclusion criteria

Exclusion criteria: 1.Patients with hypernatremia 2.Inability of the patient to sense or appropriately respond to thirst 3.Anuric patients 4.Pregnant, possibly pregnant, or nursing women 5.Patients with a history of hypersensitivity to ingredients of Tolvaptan tablets 6.Patients who are otherwise judged inappropriate for inclusion in the study by the investigators

Design outcomes

Primary

Measure	Time frame
Change of body weight	—

Secondary

Measure	Time frame
1.Change of congestive state 2.Change of urine volume, osmolarity 3.Change of plasma BNP level 4.One-Year Outcomes	—

Countries

Japan

Contacts

Public ContactKazufumi Nakamura

Okayama University Hospital Department of Cardiovascular Medicine

ichibun@cc.okayama-u.ac.jp086-235-7351

Outcome results