A Phase II Study of Carboplatin and S-1 Followed by S-1 Maintenance for Patients Who Have Squamous Cell Lung Carcinoma

A Phase II Study of Carboplatin and S-1 Followed by S-1 Maintenance for Patients Who Have Squamous Cell Lung Carcinoma - CJLSG1102

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000007433

Enrollment

Registered

2012-03-02

Start date

2012-03-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Squamous Cell Lung Carcinoma

Interventions

Carboplatin and S-1 followed by S-1 maintenance

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Better than SD after 4 cycles of S-1 plus carboplatin as initial therapy. 2) ECOG performance status (PS): 0-2 3) Adequate organ function.

Exclusion criteria

Exclusion criteria: 1) Active infection or other serious disease condition (poorly controlled diabetes mellitus, cardiac disease, Unstable angina, Cardiac infarction, Psychological illness, etc.). 2) Pulmonary disorder(idiopathic pulmonary fibrosis,interstitial lung disease,pneumoconiosis,active radiation pneumonia,etc.). 3) Massive pleural effusion, pericardial effusion, ascites, and superior vena cava syndrome. 4) Symptomatic brain metastasis. 5) Grade 2 or higher diarrhea 6) Pregnant or nursing females 7) Patients whose participation in the trial is judged to be inappropriate by the attending doctor.

Design outcomes

Primary

Measure	Time frame
12w-Disease control rate	—

Secondary

Measure	Time frame
Overall Survival, Progression Free Survival, Ratio of entering to Maintenance Therapy, Safety, Quality of Life	—

Countries

Japan

Contacts

Public ContactYoshihiro Takeyama

Toyohashi Municipal Hospital Department of Respiratory Medicine

0532-33-6111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026