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Clinical and endoscopic evaluation of the therapeutic effect of Tacrolimus with rapid dose reduction of steroid for ulcerative colitis

Clinical and endoscopic evaluation of the therapeutic effect of Tacrolimus with rapid dose reduction of steroid for ulcerative colitis - Treatment with Tacrolimus for ulcerative colitis with rapid dose reduction of steroid

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000007406
Enrollment
20
Registered
2012-04-01
Start date
2012-04-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

ulcerative colitis

Interventions

conventional steroid tapering (5mg/day every 2 weeks) rapidly tapering dose of steroid

Sponsors

Jichi Medical University Hospital Endoscopy Center
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients with relapsing ulcerative colitis with moderate to severe disease activity who admitted to Jichi Medical University hospital for induction of remission In cases with co-morbid disease or infection, the patients' condition should be stable and no changes in the therapeutic regimen for the co-morbid diseases are expected Patients who gave written informed consent for this study

Exclusion criteria

Exclusion criteria: Patients who are considered not suitable for Taclorimus use due to contraindication or considerable risks such as hypersensitivity to Tacrolimus When a written informed consent cannot be obtained from the patients because of some memory disorders such as dementia Other than above mentioned criteria, patients who are judged inappropriate by the chef study conductor or doctor in charge

Design outcomes

Primary

MeasureTime frame
Mayo Score

Secondary

MeasureTime frame
Stool frequency,rectal bleeding, Matts Score, CRP

Countries

Japan

Contacts

Public ContactHiroyuki Sato

Jichi Medical University Hospital Endoscopy Center

hiro55@jichi.ac.jp0285-58-7539

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026