Functional dyspepsia
Conditions
Interventions
None listed
Sponsors
Keio university
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients whose symptoms fullfill Rome III criteria as shown below. One or more of the following: a. Bothersome postprandial fullness b. Early satiation c. Epigastric pain d. Epigastric burning AND No evidence of structural disease(including at upper endoscopy) that is likely to explain the symptoms * Criteria fulfilled for the last 3 months with symptom onset at least 6 months prior to diagnosis
Exclusion criteria
Exclusion criteria: 1. Patients who have structural disease including erosive gastritis and GERD. 2. Patients who have history of upper GI operation 3. Patients whose causes of dyspepsia are obvious like taking much food, drink, NSAIDs, much stress, and so on. 4. Patients who have history of brain structual disease, schizophrenia, and depression. 5. Alcohol or drug dependent patients. 6. Patients who have severe disorder of endocrine system like hyperthyroidism. 7. Patients who have severe disorder of cardiovascular system, liver system, renal function, infection, and hematopoietic organ. 8. Patients who have allergic reaction for some drugs for gastrointestinal system. 9. Pregnancy or lactation woman. Patients who hope pregnancy during study. 10. Patients who took H. pylori eradication therapy within 6 months 11. Patients who are difficult to stop taking drugs like gastrointestinal drugs, anti-choline drugs, anti-depressant, and so on. 12. Suspitious for IBS 13. Any other patients which primary doctor judges them appropriate for this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| PAGI-SYM | — |
Secondary
| Measure | Time frame |
|---|---|
| Dyspepsia-related score GERDQ HADS PAGI-QOL Life-style | — |
Countries
Japan,Europe
Contacts
Public ContactHidekazu Suzuki
Department of Internal Medicine, Keio University School of Medicine Gastroenterology and hepatology
Outcome results
None listed