Parital clamping of infrahepatic inferior vena cava for reduction of blood loss during hepatectomy

Parital clamping of infrahepatic inferior vena cava for reduction of blood loss during hepatectomy - IVC partial-clamp study

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000007339

Enrollment

Registered

2012-02-20

Start date

2011-08-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

liver cancer

Interventions

Partial clamping of infrahepatic inferior vena cava Conventional method

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Patients with performance status 0-2. 2) Patients with Child-Pugh grade A. 3) Patients with well maintained bone marrow and renal functions. a) White blood cell count: 3000-12000/mm3 b) Platelet count:>=70000/mm3 c) Hemoglobin:>=10.0g/dL d) Serum creatinine:=<1.5mg/dL 4) Central venous pressure is >=5mmHg before hepatic parenchyma resection. 5) Patients who gave written informed consent prior to the study.

Exclusion criteria

Exclusion criteria: 1) Patients underwent upper abdominal surgery formerly. 2) Patients need vascular reconstruction. 3) Patients with severe cardiac dysfunction (NYHA classificaion grade III or more) or atrial fibrillation or tricuspid regurgitation. 4) Patients with deep vein thrombosis. 5) Patients with severe COPD. 6) Patients underewnt artificial dialysis.

Design outcomes

Primary

Measure	Time frame
Blood loss during surgery	—

Secondary

Measure	Time frame
Postoperative complications, change of circulating blood volume, blood loss during hepatic parenchimal resection, operating time	—

Countries

Japan

Contacts

Public ContactUeno Masaki

Wakayama medical university Sencond department of sugery

ma@wakayama-med.ac.jp073-447-2300

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026