Effects of bupropion on cognitive functions in normal subjects using fMRI

Effects of bupropion on cognitive functions in normal subjects using fMRI - Effects of bupropion on cognitive functions in normal subjects using fMRI

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000007323

Enrollment

Registered

2012-02-17

Start date

2012-02-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

healthy adults

Interventions

1day 1 time bupropion 150mg washout duration 2 weeks 1day 1 time placebo 1day 1 time placebo washout duration 2 weeks 1day 1 time bupropion 150mg

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Healthy adults. Subjects with no history of psychiatric disorders.

Exclusion criteria

Exclusion criteria: Subject with history of seizure disorders and head injury. Subject with contraindications to MRI. Subjust with drug allergy, taking drugs within 2 weeks of the trial and drinking a lot of alcohol. Woman who is breastfeeding. Pregnant woman and woman suspected of being pregnant.

Design outcomes

Primary

Measure	Time frame
Comparison of BOLD signal changes measured by fMRI between placebo and bupropion conditions.	—

Countries

Japan

Contacts

Public ContactYumiko Ikeda

Nippon Medical School Department of Pharmacology

y-ikeda@nms.ac.jp03(3822)2131

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026