Multi-institutional study of chemotherapy-associated liver injury in patients with colorectal hepatic metasasis

Multi-institutional study of chemotherapy-associated liver injury in patients with colorectal hepatic metasasis - Study of chemotherapy-associated liver injury

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000007317

Enrollment

240

Registered

2012-03-01

Start date

2012-03-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

colorectal liver metastasis

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients who have undergone second liver resection for colorectal hepatic metastasis irrespective of history of systemic chemotherapy (with more than 6 months follow-up after resection).

Exclusion criteria

Exclusion criteria: 1.Second liver resection not for the treatment of colorectal liver metastasis. 2.History of ablation therapy. 3.History of hepatic arterial infusion therapy. 4.Second liver resection after portal vein embolization.

Design outcomes

Primary

Measure	Time frame
Morbidity rate after hepatic resection according to extent of chemotherapy-associated liver injury	—

Secondary

Measure	Time frame
Exploratory investigation of pathological findings in chemotherapy-associated liver injury Risk factor for morbidity after hepati cresection	—

Countries

Japan

Contacts

Public ContactShinichiro Takahashi

National Cancer Center Hospital East Department of Hepato-Biliary Pancreatic Surgery

shtakaha@east.ncc.go.jp04-7133-1111

Outcome results