Effect of oral glucose on hemodynamics after exercise

Effect of oral glucose on hemodynamics after exercise - Effect of oral glucose on hemodynamics after exercise

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000007311

Enrollment

Registered

2012-02-16

Start date

2012-01-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

hypertensive patient, hypotensive patient

Interventions

Trial 1 (glucose ingestion): Subjects are positioned supine for 30 min before drink ingestion. The glucose drink (75g glucose in 225ml) is consumed within 1 min in raised upper body, and then subjects

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Subjects are healthy, normotensive, non-smoking, sedentary with normal activity; they perform no regular endurance training and participate in < 2 h of aerobic exercise per week.

Exclusion criteria

Exclusion criteria: Non-suitable subjects are disease, smoking, athlete with high activity; they perform regular endurance training and participate in > 2 h of aerobic exercise per week.

Design outcomes

Primary

Measure	Time frame
We evaluate the effects of 75g glucose drink on the systemic and regional hemodynamics response after dynamic exercise. Trial 1 (glucose ingestion): Subjects are positioned supine for 30 min before drink ingestion. The glucose drink (75g glucose in 225ml) is consumed within 1 min in raised upper body, and then subjects are repositioned supine for 120 min. Trial 2 (exercise): Subjects are positioned supine for 30 min before exercise. The exercise consiste of a 60-min period of upright cycling at 50% of resting heart rate reserve on 60 rpm. Immediately after the exercise period the subjects are positioned supine for a further 120 min. Trial 3 (glucose ingestion after exercise): Subjects are positioned supine for 30 min before exercise. The exercise consiste of a 60-min period of upright cycling at 50% resting heart rate reserve on 60 rpm. Immediately after the exercise period the subjects are positioned supine for a further 160 min. The glucose drink (75g glucose in 225ml) is ingested at 40 min after exercise. Blood pressure, heart rate, stroke volume and blood flows of popliteal artery, brachial artery and superior mesenteric artery are measured during the rest, post glucose and post exercise by every 10 min.	—

Measure

Time frame

We evaluate the effects of 75g glucose drink on the systemic and regional hemodynamics response after dynamic exercise. Trial 1 (glucose ingestion): Subjects are positioned supine for 30 min before drink ingestion. The glucose drink (75g glucose in 225ml) is consumed within 1 min in raised upper body, and then subjects are repositioned supine for 120 min. Trial 2 (exercise): Subjects are positioned supine for 30 min before exercise. The exercise consiste of a 60-min period of upright cycling at 50% of resting heart rate reserve on 60 rpm. Immediately after the exercise period the subjects are positioned supine for a further 120 min. Trial 3 (glucose ingestion after exercise): Subjects are positioned supine for 30 min before exercise. The exercise consiste of a 60-min period of upright cycling at 50% resting heart rate reserve on 60 rpm. Immediately after the exercise period the subjects are positioned supine for a further 160 min. The glucose drink (75g glucose in 225ml) is ingested at 40 min after exercise. Blood pressure, heart rate, stroke volume and blood flows of popliteal artery, brachial artery and superior mesenteric artery are measured during the rest, post glucose and post exercise by every 10 min.

—

Countries

Japan

Contacts

Public ContactMasako Yamaoka Endo

Prefectural University of Hiroshima Health Sciences

082-251-9770

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026