Safety and pharmacokinetic assessment of [11C]ketoprofen methylester in healthy volunteers

Safety and pharmacokinetic assessment of [11C]ketoprofen methylester in healthy volunteers - KET-1

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000007296

Enrollment

Registered

2012-02-16

Start date

2012-02-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy volunteer

Interventions

The dosage in the vein of [11C] ketoprofen methylester for PET imaging.

Eligibility

Sex/Gender

Male

Inclusion criteria

Inclusion criteria: 1. The subject who has intention to participate in this study, and singed informed consent. 2. Male subject of >=20 and <45 years old, with body weight >=50kgt and <85kg, and BMI >=17.6 and <26.4. 3. The subject who was judged by clinical investigator by means of physical examination and Laboratory tests to be eligible as a participant in this study.

Exclusion criteria

Exclusion criteria: 1)The subject who has a peptic ulcer. 2)The subject who has blood abnormality. 3)The subject who has dysfunction in the liver / kidney. 4)The subject who has cerebrovascular disorder. 5)The subject having cardiac failure. 6)The subject with WPW or LGL syndrome, or marked bradycardia, in electrocardiogram. 7)The subject with a history of a drug or food allergy. 8)The subject who was judged by the clinical investigator to be inappropriate as a participant in this study.

Design outcomes

Primary

Measure	Time frame
Safety, Pharmacokinetics, Dosimetry	—

Countries

Japan

Contacts

Public ContactMichio Senda

Institute of Biomedical Research and Innovation Division of Molecular Imaging

senda@fbri.org

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026