Effect of Aliskiren on Endothelial Function in Hypertensive Patients with Ischemic Heart Disease

Effect of Aliskiren on Endothelial Function in Hypertensive Patients with Ischemic Heart Disease - Aliskiren and Endothelial Function

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000007158

Enrollment

Registered

2012-02-01

Start date

2011-03-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypertension Ischemic Heart Disease

Interventions

Aliskiren Valsartan

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1)Hypertension 2)Ischemic heart disease 3)outpatient

Exclusion criteria

Exclusion criteria: 1)the history of allergy against aliskiren 2)diabetes HbA1C 6.5%< 3)unstabel angina, recent myocardial infaction or recent cerebral infarction (within 3 months) 4)severe liver dysfunction AST(GOT) or ALT(GPT) : 100U < 5)severe renal dysfunction Cre : 2.0< 6)pregnant 7)hyperkalemia 8) the history of drug and alcohol abuse

Design outcomes

Primary

Measure	Time frame
FMD	—

Secondary

Measure	Time frame
BP, aldosterone, CRP, urine albumine	—

Countries

Japan

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026