Ischemic Heart Disease Congestive Heart Failure Chronic Kidney Disease Peripheral arterial Disease
Conditions
Interventions
The control patients were applied intravenous hydration with 0.9 % isotonic saline at a rate of 1ml per kilogram per hour (or 0.5ml per kilogram per hour in the case of low ejection fraction lesser th
Sponsors
Yokohama Medical Center (Department of Clinical Research)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: The patients who are scheduled for cardiovascular angiography including diagnostic coronary angiography, ventriculography, aortography, and/or coronary or peripheral intervention.
Exclusion criteria
Exclusion criteria: peritoneal dialysis, hemodialysis treatment, cardiogenic shock, congestive heart failure, pregnancy, a history of severe allergies to contrast media, recent major bleeding, having a metformin within 48 hours of the study entry, chronic obstructive pulmonary disease, patient with the oxygen saturation lesser than 90 percent, acute coronary syndrome, severe infection, severe malnutrition, post-operative states, pituitary or adrenal dysfunction, paraquat intoxication
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Contrast-Induced Nephropathy : defined as an increase in the serum creatinine concentration of 25 percent or 0.5 mg/dl from the baseline at maximum value obtained within 48 hours after the procedure | — |
Secondary
| Measure | Time frame |
|---|---|
| sex, age (more than 70-year-old), hypertension, diabetes mellitus, dyslipidemia, a history of myocardial infarction, BNP(more than 100pg/ml), anemia, use of ACE inhibitors/ARBs, use of diuretics, use of statins, use of contast-medium (more than 150ml), eGFR (less than 60ml/min/1.73m2), PaO2 (more than 100 mmHg) As sub-analysis, among the patients with eGFR under 60ml/min/1.73m2 for CIN high risk group. | — |
Countries
Japan
Outcome results
None listed