Effect of esomeprazole on symptom relief in patients with PPI-refractory GERD

Effect of esomeprazole on symptom relief in patients with PPI-refractory GERD - Effect of esomeprazole on symptom relief in patients with PPI-refractory GERD

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000007116

Enrollment

100

Registered

2012-01-23

Start date

2012-01-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

PPI-refractory GERD

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Patients with IC 2. Diagnosis as having reflux esophagitis by endoscopy during the past 12 months 3. 2-3 days and more in atleast one of Q1, Q2, Q5, Q6 of GerdQ

Exclusion criteria

Exclusion criteria: 1. Esomeprazole allergy 2. Prescribing atazanavir sulfate 3. Esophageal stricture, IBS, IBD, Zollinger-Ellison syndrome, Malabsorption syndrome 4. Active gastric or duodenal ulcer by endoscopy 5. Sever Heart, kideny, liver diseases 6. Upper GI surgery 7. Pregnancy 8. PPI administration 14 days before trial 9. Co-treatment with H2RA, prokinetcis, other PPI etc. 10.Other drugs (diazepam, digoxin, etc.)

Design outcomes

Primary

Measure	Time frame
Imrovement rate in GerdQ 4 weeks after esopmerazole treatment	—

Countries

Japan

Outcome results