No (healthy donor)
Conditions
Interventions
control (starch tablet) intake one tablet per day for four weeks
five hundred-millions of lactobacilli in one tablet intake one tablet per day for four weeks
fifteen hundred-millions of lactobac
Sponsors
Department of Molecular-Targeting Cancer Prevention, Kyoto Prefectural University of Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Healthy adult men and women
Exclusion criteria
Exclusion criteria: 1. people with chronic diseases (allergic disease, hypertension, hypotension, diabetes, hyperuricemia, chronic bronchitis, emphysema pulmonum, thyroid deficiency, osteoporosis, angina, chronic hepatitis, chronic pancreatitis, rheumatism) 2. people while taking (lactobacillus preparation, immune-suppressing drug) 3. women in pregnancy, woman of child-bearing potential or lactating woman 4. people in a clinical trial or in passing not over four weeks from end of clinical trial
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes of expression of specific cytokine related to cancer prevention in plasma, saliva, urine and PBMC from the participants after intervention with/without lactobacilli | — |
Countries
Japan
Outcome results
None listed