Evaluation of relationships between hepatic steatosis and sleep apnea in subjects suspected to have abdominal obesity, and effects of CPAP treatment on hepatic steatosis.

Evaluation of relationships between hepatic steatosis and sleep apnea in subjects suspected to have abdominal obesity, and effects of CPAP treatment on hepatic steatosis. - Hepatic steatosis, sleep apnea and effects of CPAP therapy.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000007112

Enrollment

Registered

2012-01-21

Start date

2013-02-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

obstructive sleep apnea, hepatic steatosis

Interventions

CPAP (Continuous Positive Airway Pressure)

Eligibility

Sex/Gender

Male

Inclusion criteria

Inclusion criteria: (1) Evaluation of relationships between hepatic steatosis and sleep apnea # Those who underwent polysomnography for suspicion of sleep apnea, and underwent abdominal CT at the time of polysomnography or before the introduction of CPAP (The target sample size is 200). (2) Evaluation of effects of CPAP on hepatic steatosis # Those who were introduced CPAP therapy for diagnosis of obstructive sleep apnea by the polysomnography described above. # Those who were diagnosed to have abdominal obesity at the baseline evaluation. # Six months or more elapsed from the introduction of CPAP.

Exclusion criteria

Exclusion criteria: # Those who have positive serological HBs antigen, positive serological HCV antibody, or liver disease other than fatty liver. # Those who have other serious complications. # Those whose blood BNP levels are 100pg/ml or more. # Those who take drugs which may cause of hepatic steatosis (amiodarone, methotrexate, systemic steroids, etc.)

Design outcomes

Primary

Measure	Time frame
CT attenuation of liver	—

Countries

Japan

Contacts

Public ContactYoshiro Toyama

Kyoto University Graduate School of Medicine Department of Respiratory Care and Sleep Control Medicine

ytoyama@kuhp.kyoto-u.ac.jp075-751-3852

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026