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Efficacy of tacrolimus in patients with refractory nephrotic syndrome

Efficacy of tacrolimus in patients with refractory nephrotic syndrome - Efficacy of tacrolimus in patients with refractory nephrotic syndrome

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000007089
Enrollment
20
Registered
2012-01-17
Start date
2012-01-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Refractory nephrotic syndrome

Interventions

Administration of 0.05mg ~ 0.15mg/kg/day tacrolimus, and the target trough concentration of 5 to 10ng/ml. Administered to taclolimus until an effect is seen.

Sponsors

Department of Nephrology and Hypertension, Saitama Medical Center,Saitama Medical University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: The patient is resistant to treatment in the guidelines on nephrotic syndrome

Exclusion criteria

Exclusion criteria: Significant renal dysfunction (Cr> 5mg/dl)

Design outcomes

Primary

MeasureTime frame
decrease in proteinuria, improvement of serum albumin, improvement of GFR etc

Countries

Japan

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026