Refractory nephrotic syndrome
Conditions
Interventions
Administration of 0.05mg ~ 0.15mg/kg/day tacrolimus, and the target trough concentration of 5 to 10ng/ml. Administered to taclolimus until an effect is seen.
Sponsors
Department of Nephrology and Hypertension, Saitama Medical Center,Saitama Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: The patient is resistant to treatment in the guidelines on nephrotic syndrome
Exclusion criteria
Exclusion criteria: Significant renal dysfunction (Cr> 5mg/dl)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| decrease in proteinuria, improvement of serum albumin, improvement of GFR etc | — |
Countries
Japan
Outcome results
None listed