Dental patients
Conditions
Interventions
Group M: Intravenous administration of midazolam at dose of 0.02mg/kg. 1. We select subject from patients for whom the doctor has ordered intravenous sedation. Inclusion criteria is SBP>
=140mmHg or DBP>
=90mmHg measuring when the patient sits on dental chair and has settled down for 5 minutes. Informed consent is obtained from the patient. 2. Patient conducts Japanese version of STAI and VAS about a
Sponsors
Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Inclusion criteria is SBP>=140mmHg or DBP>=90mmHg measuring when the patient sits on dental chair and has settled down for 5 minutes among dental outpatients scheduling intravenous sedation with American Society of Anesthesiologists physical status I or II.
Exclusion criteria
Exclusion criteria: 1.Uncontrolled or unstable hypertension 2.Secondary hypertension such as hyperthyroidism and pheochromocytoma 3.Taking sympathomimetic drugs 4.Contraindication of midazolam such as myasthenia gravis and acute narrow-angle glaucoma 5.A pregnant woman or during lactation period 6.Psychiatric disorder such as schizophrenia 7.Not having intelligence enough to read, understand and write a Japanese version of STAI 8.Judged unsuitable by a researcher
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Blood pressure, heart rate, and oxygen saturation before and 2,4,6,8,10 minutes after drug administration. Japanese version of STAI before and 10 minutes after drug administration. | — |
Secondary
| Measure | Time frame |
|---|---|
| Visual analog scale about anxiety to dental treatment. Sedation level. | — |
Countries
Japan
Contacts
Public ContactYoshihisa Watanabe
Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences Department of Dental Anesthesiology and Special Care Dentistry
Outcome results
None listed