Randomized controlled trials for the efficacy between famotidine alone and combination of famotidine and egualen sodium hydrate on gastric ulcer healing for following eradication therapy for Helicobactor pylori

Randomized controlled trials for the efficacy between famotidine alone and combination of famotidine and egualen sodium hydrate on gastric ulcer healing for following eradication therapy for Helicobactor pylori - The effect of egualen sodium hydrate on gastric ulcer healing for following eradication therapy for Helicobactor pylori

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000007010

Enrollment

100

Registered

2012-01-04

Start date

2010-10-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gastric ulcer for following eradication therapy for Helicobactor pylori

Interventions

Famotidine 20mg twice per day 8 weeks Famotidine20mg twice per day +Egualens sodium hydrate15mg twice per day 8 weeks

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1.Helicobactor pylori infected patients diagnosed with peptic ulcer by endoscopic examinations 2.Patients with active gastric ulcer(A1/A2) 3.Patients whose diameter of ulcer is 1.5cm or longer 4.Patients of 20 year or older 5.Patients who can understand the consents of this trial is obtained in written form.

Exclusion criteria

Exclusion criteria: 1.Patients with drug allegy 2.Patient taking Atananavir sulfate,Pimozide and Ergatamine-containing drugs 3.Patient who has been mononucleosis 4.Patients with severe liver and renal dysfunction, and serious heart-lung complication. 5.Pregnant, females who suckles, or females who wish to become pregnant 6.Patients who have eradication therapy of Helicobactor pylori infection 7.Patient who take PPI or H2RA within 1 month before obtaining informed consent 8.Patients who take mucosal protective medicine within 2 weeks before obtaining informed consent 9.Others,patients who are judged to be inadequate to participate in this trial by the investigator

Design outcomes

Primary

Measure	Time frame
The healing rate of gastric ulcer within 8 weeks	—

Secondary

Measure	Time frame
The healing rate of gastric ulcer after 8 weeks QOL score (GSRS) after 2 weeks and 8 weeks	—

Countries

Japan

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026