Invasive pneumococcal disease, Pneumonia, Acute otitis media
Conditions
Interventions
None listed
Sponsors
Takao Fujisawa
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: S.pneumoniae strains isolated from the following disease. 1)Invasive Pneumococcal Disease(IPD) Requirement; 1:Diagnosed as Bacterial meningitis, Bacteremia, Pneumonia, Arthritis, Peritonitis 2:S. pneumoniae is isolated from physiologically sterile site [spinal fluid, blood, tissue fluid]. 3:Age: over 2 months and under 16 years old 2)Pneumonia Requirement; 1:Diagnosed as Pneumonia by chest X-ray, the following symptoms are observed: pyrexia, cough, dyspnea, chest pain, general malaise and/or sputum 2:Age: over 2 months and under 5 years old. 3:S.pneumoniae is isolated from sputum according to the reference article method. 3)Acute otitis media [AOM] Requirement; 1:Diagnosed as AOM by the clinical symptoms and tympanic membrane findings. 2:Age: over 2 months and under 5 years old. 3:S.pneumoniae is isolated from specimen which is collected by Myringotomy or paracentesis of the tympanic membrane. 4:For avoiding contamination by Myringotomy, the specimen is collected by seed-swab.
Exclusion criteria
Exclusion criteria: None
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1) Capsular serotype of clinically isolated S.pneumoniae 2) Minimum inhibitory concentration (MIC) of these isolates 3) MLST(Multilocus sequence typing) | — |
Countries
Japan
Contacts
Public ContactMiwa Izutsu
CTD inc. Pneumocatch research office
Outcome results
None listed