Effect of Intensive LDL-C Lowering with High-dose Atorvastatin on Inflammation and Postoperative Organ Damage in Patients Undergone Coronary Artery Bypass Surgery

Effect of Intensive LDL-C Lowering with High-dose Atorvastatin on Inflammation and Postoperative Organ Damage in Patients Undergone Coronary Artery Bypass Surgery - Effect of high-dose Atrovastatin on inflammation

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000006879

Enrollment

Registered

2012-01-01

Start date

2012-01-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

coronary artery disease

Interventions

20mg/day of Atrovastatin Starting-dose statin

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: patients undergoing elective primary isolated coronary artery bypass surgery

Exclusion criteria

Exclusion criteria: Hemodialysis Undergoing with intensive statin therapy Stroke or acute myocardial infarction Emrgerncy/Urgent surgery Sever liver dysfunction Pregnancy (including suspected) Allergy or history of allergy

Design outcomes

Primary

Measure	Time frame
Expression of inflammatory cytokines and adipocytekines from each adipose tissues	—

Secondary

Measure	Time frame
Lipid profiles, inflammatory markers, adipocytekines and blood cell counts in peripheral blood	—

Countries

Japan

Contacts

Public ContactTaira Yamamoto

Juntendo University Hospital Department of Cardiovascular surgery

tyamamo@juntendo.ac.jp0338133111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026