A clinical study that investigates the ability of the HIRA-TAN to shorten the time required for the transition from an empiric therapy to a specific therapy in adult pneumonia.

A clinical study that investigates the ability of the HIRA-TAN to shorten the time required for the transition from an empiric therapy to a specific therapy in adult pneumonia. - Early initiation of specific therapy with HIRA-TAN

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000006863

Enrollment

1000

Registered

2011-12-08

Start date

2011-12-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

pneumonia

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: All inpatient and outpatient with pneumonia (aged 18 and older) who fulfill the criteria 1-4 and provid sputum classified as Miller and Jones M2, P1, P2 or P3. 1. Gram stain and culture of expectorated sputum is submitted before the treatment. 2. Urine antigen test for S. pneumoniae is submitted. 3. Blood sample for bacterial culture and Urine antigen test for L. pneumophila are submitted(cases that admit to the hospital only). 4. Influenza antigen test is submitted(flu season only).

Exclusion criteria

Exclusion criteria: Patients that do not fulfill the inclusion criteria.

Design outcomes

Primary

Measure	Time frame
Investigation on the ability of the HIRA-TAN to shorten the time required for the transition from an empiric therapy to a specific therapy.	—

Secondary

Measure	Time frame
Comparison of the overall performance of HIRA-TAN system and conventional method to identify the causative pathogen of pneumonia. Comparison of the cost between HIRA-TAN system and conventional method required for identification of the casative pathogen of pneumonia. Validity of the cutoff values that identify pathogenic roles of the commensal organisms in pneumonia; the organisms include S. pneumoniae, H. influenzae, M.catarrhalis, P. aeruginosa, A. baumannii, S. maltophilia, S. aureus, E. coli and S.marcescens.	—

Measure

Time frame

Comparison of the overall performance of HIRA-TAN system and conventional method to identify the causative pathogen of pneumonia. Comparison of the cost between HIRA-TAN system and conventional method required for identification of the casative pathogen of pneumonia. Validity of the cutoff values that identify pathogenic roles of the commensal organisms in pneumonia; the organisms include S. pneumoniae, H. influenzae, M.catarrhalis, P. aeruginosa, A. baumannii, S. maltophilia, S. aureus, E. coli and S.marcescens.

—

Countries

Japan

Contacts

Public ContactTakashi Hirama

Saitama Medical University Respiratory medicine

mycobacteriumtuberculosis@hotmail.com+81-49-276-1319

Outcome results